Step 2: Tap the power button to turn it back on. Step 1: Power off your PC by holding the power button. Here's how to boot your PC into Safe Mode if your mouse and keyboard aren't working. Try booting your computer into Safe Mode and try the troubleshooting options listed below (1 to 4). According to some Windows users who have encountered his issues in the past, they were able to use both the mouse and keyboard in Safe Mode.
